Identification And Characterization Of Amorphous Silica

The inhalation of dust has been a problem in the mining industry since antiquity. Crystalline silica is now known to be the cause of silicosis, a form of pneumoconiosis that is associated with excessive exposure to respirable particles in some mining and industrial environments. Crystalline silica was reviewed by the International Agency for Research on Cancer (IARC) in 1986 and classified as a Group 2A, Probably Carcinogenic to Humans in Volume 42 and Supplement 7 of the IARC Monographs (1987). In 1996, IARC reviewed additional literature and studies published in the intervening decade and recommended that quartz and cristobalite, two polymorphs of crystalline silica, be listed as Group 1, Carcinogenic to Humans. Their recommendations and reclassification were published in 1997 in IARC Monographs 68.[2] In both Monographs, IARC classified amorphous silicas as Group 3, Inadequate Evidence for Carcinogenicity to Humans.