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By Y. H. Cheng, D. M. Lewis, V. Castranova, M. W. Barger, J. K. H. Ma, J. Y. C. Ma, W. F. Xin

Bis-basic ethers off fluorene and fluoren-9-substituted derivatives such as tilorone have been reported to inhibit silica-induced fibrosis in rats. The potential antifibrotic potency of 2,7-bis (diethylamino) ethixy fluorine fluorenone (F-9-H.H), fluorenoxime (F-9-one), and fluorenol (F-9-ol) was F-9-axime > F-9-one ~ F-9-H,H > F-9-ol. Since the release of reactive oxygen species and growth factors from alveolar macrophages (AM) in response to silica exposure has been linked to the development of pulmonary fibrosis, the present study was carried out to determine the inhibitory effects of these compounds on rat AM activity in vitro. The following parameters were monitored: (1) cellular viability; (2) zymosan-induced respiratory burst activity (superoxide and hydrogen peroxide release, chemiluminescence, and oxygen consumption) of AM; (3) drug binding to AM; and (4) lipopolysaccharide (LPS)-stimulated interleukin- I (IL-1) release from AM. The bis-basic ethers, at 40 did not affect cell viability when incubated with AM for 30 min, but significantly inhibited zymosan-induced macrophage respiratory burst activity. The inhibitory effect of these agents was F-9-oxime > F-9-one ~F-9-H,H > F-9-ol. Binding of these drugs to AM was time and dose dependent, and exhibited the following binding affinity: F-9-oxime > F-9-one > F-9-H,H > F-9-ol. F-9- oxime was shown to inhibit LPS-stimulated IL-I release by AM in a dose-dependent manner. This inhibition of IL-1 release by AM cannot be explained as a decrease in viability. In addition, these drugs were also shown to impair human fibroblast proliferation in response to serum stimuli without impairing cell viability. These results indicate a positive correlation between drug binding to AM or other cell types and their inhibitory effects on cellular activities including oxygen consumption, superoxide release, hydrogen peroxide secretion, chemiluminescence, IL-I release, and proliferation. The ability of-these bis-basic ethers to modify AM and fibroblast functions in vitro suggests that further investigation of their reported antifibrotic potency in vivo is warranted.

Dec 1, 1996

By John M. Dale

Now that the price of sulfur has reached unexpected high levels, it is little wonder that sulfur from surface ores is again receiving attention. In most instances, it is advantageous for an ore to be at or near the surface. However, it is a distinct disadvantage for sulfur ore to be close to the surface because it precludes the use of the Frasch process. The Frasch process depends on the presence of at least 180 m of uniform overburden to allow pressure injection of superheated water into the sulfur-bearing formation to melt the sulfur. In the Frasch process, sulfur separates cleanly from the gangue underground and comes to the surface in a very pure form. Surface sulfur deposits, particularly those in the Western Hemisphere, exist largely due to volcanic activity, and sulfur separation from the gangue is a formidable technical problem. None of the surface deposits are large compared to some of the Frasch deposits, but at the present sulfur price, they are certainly of economic importance. From the turn of the century until 1975, the price of sulfur was for the most part $18-$28/t. However, with the price of sulfur now over $154/t, there are a variety of technical alternatives to consider for sulfur surface ore separation that may not have been economically attractive a few years ago.

Jan 9, 1981

By A. Bothma

The Impala No. 1A ventilation shaft is located approximately 15 kms north of Rustenburg and is accessed via the R510road from Rustenburg to Northam/Thabazimbi. This situation is shown on the location plan in Figure 1. The geology at the site consists of an upper layer of black turf of about 1 metre in thickness, grading into weathered norite. The depth of weathering is generally less than 5 metres. Zones of deeper weathering may occur along fracture zones associated with faults and dykes. Groundwater occurs mainly within the weathered/fractured aquifer system. The ventilation shaft is a 5.1 m diameter upcast shaft ,and forms part of a system of ventilation shafts to complement the existing infrastructure as mining progresses down the new twin decline extension of Impala 1 shaft. The principal reason for these shafts is to lessen the risk of an extended RAW and also to counter the effects of the heat build-up as the mining goes deeper, with the resultant effect that the existing cooling centre (fridge plant) becomes more remote from activities. The No. 1A shaft (upcast) is positioned approximately 1,2 km on down dip from the main shaft and the No. 1Bshaft (downcast) approximately 1,2 km further. Geological information was used from a borehole 1,2 km away on strike from the upcast shaft. The first shaft (1A) is a 5,1 m diameter hole to be fitted with two 2,2 MW fans, whilst the second shaft (1B) is 4,1 m diameter to accommodate a 7MW fridge plant.

Jan 1, 2001

By M. Nete

Qualitative analysis of three mineral samples from northern Mozambique was accomplished by X-ray diffraction (XRD), microscopy, scintillation, and magnetic determination. Chemical characterization was accomplished using ICP-OES and pressed powder XRF after dissolution using microwave-assisted digestion and flux fusion. The samples consisted of a mixture of minerals with tantalite as the major component, with minor amounts of microlite, quartz, mica, accessory garnet, and tourmaline. Incomplete dissolution was obtained using microwave digestion, with maximum recoveries of 90.25 ± 0.06% and 88.90 ± 0.04% for Nb2O5 and Ta2O5 respectively. Complete dissolution using Li2B4O7 resulted in recoveries of 98.5 ±0.2% Nb2O5 and 100.4 ± 0.3% Ta2O5.

Jan 1, 2012

By R. L. Andrew

The southwest Pacific has produced at least four of the world’s premier porphyry copper-gold deposits, and the current level of exploration is likely to produce even more. An appreciable amount of gold is being produced with this copper, with obvious economic advantages. Gold content, in addition to their large size, makes the southwest Pacific’s porphyrycopper-gold deposits very attractive exploration targets. The recognition of telescoping and overprinting of porphyry systems has produced a greater awareness of the likely surface expressions, in particular the significance of advanced argillic lithocaps in porphyry exploration. The recognition of the spatial and genetic association of porphyry copper and epithermal gold systems (Sillitoe, 1972), as in other parts of the world, has had important implications for exploration in the Asia Pacific region.

Jan 1, 1995

By Dan A. Brown

This paper describes a method of conducting rapid lateral loading tests of deep foundations in which the load is applied to the foundation with a time duration of less than one second. For purposes of this paper the loading is applied using a pyrotechnic loading system commonly referred to as Statnamic. However, the method should apply to any lateral loading system which produces a force time history with a loading duration of 20 msec to 1 second. The test provides a measure of the dynamic and static response of the soil/foundation system and must be evaluated as a dynamic loading. Interpretation of the test includes a simple single degree of freedom (SDOF) model which can account for the inertial effects of foundation mass, system damping, and static foundation stiffness. The results of the test measurements are compared with four case histories in which comparative static load test data are available, including pile group foundations and large diameter drilled shaft foundations.

Jan 1, 2007

By T. A. E. Breen

A new high intensity grinding technology has been developed and is now being commercialized by Hicom International of Australia. This has led to the development and manufacture of Hicom 120 grinding mills which are now being sold internationally for a range of mining industry applications. The first commercial process application has been for the diamond sector, where the ability of the mill to remove host kimberlite rock by attritioning, with no damage to the thereby liberated diamonds, is seen to be a most beneficial attribute. There are, however, many other mineral industry applications for this mill. The design of the Hicom mill is unique. Based on a high speed centrifugal motion of the grinding chamber, very high power intensity is delivered to the grinding process. Most significantly, a high acceleration field, 50 times stronger than gravity is produced, creating very high power input per unit of mill volume, and exceptionally fast particle breakage rates, typically 50 - 100 times greater than those in conventional tumbling mills. A mill developing such forces has significant implications to comminution technology and practice.

Jan 1, 1999

By Jose R. Hernandez-Aguilar, Chris J. Martin, Rob Thorpe

"This study presents an approach to establishing relationships between metallurgical performance and the characteristics of the bubble population (gas dispersion) inside flotation cells. Bubble size Db, superficial gas velocity Jg, and bubble surface area flux Sb (Sb = 6Jg/Db) measurements were obtained along with metallurgical samples in full-size equipment processing different ore types. The gas dispersion was manipulated by changing the operating conditions of the cells (gas flowrate and frother type) and the metallurgical performance (grade-recovery) was determined. In two cases, the Sb had a strong relationship with grade and recovery, hence, Sb could be used as practical operating parameter. In another case, Sb did not correlate with recovery. The reasons were attributed to creating small bubbles using frothers with desired anti-coalescence properties. This illustrated that bubble size was the key parameter for metallurgy rather than Sb.INTRODUCTIONUnravelling the mechanisms that govern the relationships between metallurgical performance and the characteristics of the bubble population (gas dispersion) inside a flotation cell remains a major challenge. Information on this subject is scarce in the literature, particularly, plant-scale data. The report of Jameson and Allum (1984) appears to be the first gas dispersion study conducted in industrial (mechanical) cells. To introduce concepts, some aspects of their work are reviewed here.The prime motivation of that study was to establish whether any particular cell design (among 44 cells surveyed) could produce very small bubbles (< 0.1 mm), which laboratory research suggested would increase the recovery of fine particles. Although one of the outcomes was that the (examined) cells did not seem to produce such small bubbles (Sauter mean1 D32 ˜ 0.9 mm), the analysis highlighted the importance of including other factors. Jameson and Allum indicated that, besides bubble size (Db), other characteristics of the bubble dispersion should be considered, namely: gas holdup ?g – the fraction of cell volume occupied by bubbles, superficial gas velocity Jg – is the gas flowrate divided by the cross-sectional area of the cell and, bubble surface area flux Sb – the rate of production of (new) bubble surface area (m2/s) per m2 of cell cross-sectional area. It should be noted that, whereas Jg, ?g and Db can be measured directly, the Sb is derived: Sb = 6Jg/Db, where Db is usually substituted by the Sauter mean diameter (D32)."

Jan 1, 2006

By F. Malek

At Creighton Mine, magnitude events are a regular occurrence due to depth and major seismically-active structures. Over the last ten years, major advances have been made in research and development to develop strategies for the management of these major events. Today, the number of rockbursts has been drastically reduced at the mine and damage due to seismic events, when they occur, is often minimal. This paper describes the evolution and implementation of appropriate geomechanics strategies, designs, and practical ground control measures undertaken for the management of seismicity at Vale Inco?s Creighton Mine. A description of the research and development approach, implementation, and ground control strategy is provided for placement of enhanced support systems to manage the consequences of magnitude events at Creighton

May 1, 2009

By James C. Barker

Unverified reports of rare earth element (REE) concentrations in gold placers and radioactive mineral prospects in the Zane Hills were investigated by the U.S. Bureau of Mines as part of the Alaska critical minerals program. REE is reported to occur in dredge concentrates at the Hogatza mine and up to 1.2 pct REE was previously analyzed in alkalic syenite (bostonite) dikes marginal to the pluton. In addition, numerous thorium-rich veins, explored for their uranium content but unevaluated for REE, occur on the western margin of the Zane Hills. The Bureau mapped and sampled all of the reported or suspected REE occurrences. Dredge concentrates contain abundant uranothorianite, a mineral species which incorporates cerium subgroup REE. Bostonite dikes occur in conjunction with a multi-phased zoned alkalic intrusion, however, no significant REE concentrations were found. Thorium-rich veins contain nil to 0.5 pct Y but resource potential is limited by this relatively low grade, the ultimate low tonnage potential, and the lack of uranium as a major economic element. The Zane Hills exhibit attractive exploration targets for uranium deposits, primarily in a sedimentary form. Gold may be found peripheral to the pluton in both placer and lode deposits. Resource potential of REE, however, appears limited to a placer by-product of REE-Zr-Ti that is recoverable only during large scale gold placer mining. Placer exploration of the lower Wheeler and Dakli Creeks is suggested.

Jan 1, 1991

By Sachihiko Tokunaga, Hirofumi Taguchi, Kenji Maruyama, Hidenori Takahashi, Yoshiyuki Morikawa

"Abstract The present study proposed a new liquefaction countermeasure to improve sandy ground and conducted a trial execution. The new method is a floating-type and lattice-shaped cement treatment method, where cement-treated soil is not fixed to a non-liquefiable stratum. A fixed structure such as treated soil should be formed at the side of the floating-type treated soil to reduce its lateral displacement. In the study, one-dimensional dynamic response analyses were first conducted to confirm the mechanism of the new method. Then, a series of centrifuge model tests were performed to demonstrate the effect under a stress condition at the prototype scale. The analyses and model tests confirmed the effect of the liquefaction countermeasure. Finally, trial executions were carried out to confirm high-quality vertical execution.INTRODUCTIONLiquefaction induced by an earthquake generates sand boiling and ground settlement. Other problems have also been reported, including a decrease in bearing capacity and an increase in the horizontal earth pressure against retaining walls. To prevent these problems caused by liquefaction of the ground, various countermeasures have been proposed, such as cement deep mixing and high-pressure jet mixing methods. These methods have the big advantage of being applicable to ground that contains soil with a fine-grain fraction. Furthermore, the unnecessary displacement caused by the construction can be reduced. In Japan, a lattice-shaped cement-treatment method has frequently been used at many construction sites to prevent liquefaction, where cement-treated piles are intersected to form a lattice, as shown in Fig. 1. The lattice-shaped walls can reduce the shear stress generated by an earthquake, restricting the liquefaction at that location. However, the construction cost of the cement treatment is relatively high compared to other methods such as the sand compaction pile (SCP) method, and needs to be reduced. In particular, the cost of the high-pressure jet mixing method, which can be applied to the liquefiable ground under existing structures, is significantly high. Therefore, decreasing the total volume of the cement treatment is necessary to reduce the construction cost."

Jan 1, 2014

By Georgene Renner, William R. Yernberg, William Gleason

American Commercial (ACI) offers a selection of ground control solutions. Beginning with steel liner plates installed in the Gratiot Avenue sewer system in Detroit, MI 1920, ACI is one of the leading designers and manufacturers of underground steel supports in North America. ACI is also a leader in fire-proofing underground structures with its Promat Fire Protection Boards. The sandwich panels have been used in many new and retrofit tunnel and underground construction projects worldwide. Ease of installation and replacement, cost effectiveness and superior performance have made this product line the premier choice of owners and designers for structural protection, fire-life safety requirements and architectural finish needs.

Jan 1, 2007

By S. J. S. Ferreira

Anglo American Platinum&apos;s Khomanani 2 shaft changed over from down-dip mining to breast mining in 2004. The changeover was made to ensure that production targets were met, as it was said that predevelopment for down-dip mining was not fast enough to sustain the required ore reserves; nevertheless, production performance did not increase as expected. In this study a trade-off was performed between down-dip mining and breast mining on the Merensky Reef at Khomanani 2 in order to find the most suitable method for mining the Merensky Reef. Data was gathered by means of a literature survey, underground observations, and interviews with personnel as well as data from various departments on the mine. The two mining methods were studied and then evaluated in terms of the following criteria: safety, mining rate, cost and other factors which were identified as the main drivers of the mine. A scaling system was used to rate the performance of the two mining methods. Analysis of the results shows that down-dip mining and breast mining have the same safety performance ratings. Breast mining has a better mining rate performance than down-dip mining. Breast mining was found to be costly in comparison with down-dip mining, which has a good cost performance rating. The overall ratings of the two mining methods are very similar, with down-dip mining achieving a rating of 76 and breast mining 75.5 out of an optimum 102. Khomanani 2 currently practices breast mining, and with such a slight difference in performance rating between the two methods, it will not be worth changing over to down-dip mining as production is likely to be adversely affected during the changeover. Down-dip mining does, however, have potential for improvement in its performance rating. Further studies focusing on the improvement of the mining rate performance for down-dip mining are needed to see if this potential can be realized. If significant improvement can be made in the performance rating for down-dip mining, a changeover to down-dip mining can be reconsidered.

Jan 1, 2012

By Zhang Baoshan

In this paper, the forced features and dynamic behaviors of stone-column composite foundation are concisely related. The characteristics of Rayleigh wave method is summarised. This method is proposed in which, the stress ratio of the stone-column to the surrounding soil and the bear­ing capacity of the composite foundation are determined. Through the engineering cases, it is shown that, checking and evaluating the composite foundation in this method, is feasible, with high speed and low cost.

Jan 1, 1991

By John Dasher

In 1980, some US cars were designed and built to metric dimensions; wine and gas were sold by the liter; and the March of Dimes Walkathon was measured in kilometers. Although the US Congress has taken a &apos;&apos;soft" approach to metrication, and public resistance to the idea remains strong, the use of metric units is becoming more and more widespread. As the minerals industry becomes more international in scope, US mining companies are converting to the metric system-particularly those companies with business interests overseas.

Jan 2, 1981

By Barrick Pierina, John Frostiak, Igor Gonzales, Kenneth G. Thomas, Ken Manning

"1.0 SummaryThe Pierina deposit was acquired in August 1996 when Barrick Gold Corporation purchased Arequipa Resources, a junior mining company with extensive land positions in Peru. At the time of acquisition, Arequipa had developed two exploration tunnels and drilled 9 exploration holes on the property. Metallurgical tests, conducted on samples taken from the tunnels and the exploration holes indicated that the ore was amenable to heap leaching. Barrick’s exploration team recognised from the outset, the potential of the mineralisation and convinced Barrick’s senior management that this was indeed a world class deposit that should be pursued. On November 25, 1998, the first dore was poured at Pierina, 27 months from the time of acquisition. During that period Barrick completed its exploration programme, prepared a development plan including capital and operating costs, production profiles and cash flow forecasts, and a schedule to develop a mine and construct a leach pad and gold recovery plant, including all supporting infrastructure. All permits and environmental approvals were obtained and all necessary land was acquired. The project was completed on schedule and under budget. This was the first greenfield mine development for Barrick outside of North America.This paper details, mainly, the research and development, engineering, construction and commissioning of the metallurgical process facilities.2.0 The Develonment ProgrammeImmediately after the acquisition, Barrick began the process of gathering information required to prepare a project development plan. Kilborn Engineering was retained to assemble all of the information collected and collated into a development plan document. This document was completed by June 16,1997. The objective was to bring the mine into production as quickly as possible with critical activities identified as follows:"

Jan 1, 2000

By A. Butler

This paper explains the politics of mine nationalization in contemporary South Africa. Nationalization and privatization typically occur in the oil, mineral resources, and state utilities sectors, and they tend to follow one another in a long-term cyclical pattern. The paper explains why the current international environment has encouraged demands for nationalization and other forms of ?resource nationalism? in the South African minerals sector. It goes on to describe how the resurgence of resource nationalism has been influenced by internal factional politics in the African National Congress. It concludes that nationalization is unlikely to be the outcome of current policy deliberations within the ANC.

Jan 1, 2013

By Doug Tesarik

Researchers from the National Institute for Occupational Safety and Health1 (NIOSH), together with employees from The Doe Run Company, are monitoring and evaluating the stability of a pillar retreat section at the Fletcher Mine, a lead/zinc, room-and-pillar mine near Bunker, MO. Cemented rockfill is being used to provide roof support as high-grade, remnant ore pillars are mined. Earth pressure cells and deformation meters placed in backfill panel pillars monitor stress change and vertical deformation, respectively, as nearby ore-bearing pillars are extracted. Similarly, biaxial stressmeters and borehole extensometers are used to monitor mining-induced stress change and deformation, respectively, in long-term support pillars. Data from these instruments indicate that when ore-bearing pillars were mined, stress was redistributed from support pillars to a backfill panel pillar. The data also indicate that the backfill and support pillars have remained stable for two years after pillar extraction was completed in the area. This research demonstrates the importance of using reliable instruments to document the geomechanical behavior of pillars and backfill. Gaining a better understanding of roof support and stress redistribution mechanisms is a fundamental part of NIOSH&apos;s goal to reduce and/or predict rockfalls, which are still among the leading causes of injuries in metal/nonmetal underground mines.

Jan 1, 2006

By Ganesh Kumar S.

"Soil reinforcement using stone columns is one of the well-developed ground improvement techniques for soft clay deposits. The load carrying capacity can be further improved by encasing it with geosynthetic material around the column which offers effective lateral confinement, prevents column contamination with improved drainage and strength characteristics. Improvement of undrained shear strength using vacuum consolidation is a type of hydraulic modification technique in which negative pore pressure will be developed which increases the effective stresses in soil without changing the total stress. The improvement in effective stress resulted in improved undrained shear strength of surrounding soil. In this research work, combined geosynthetic encased stone column and vacuum treatment method is examined for improving of extremely soft clay soils. The improvement in the time rate of consolidation and load carrying capacity of stone columns after vacuum treatment was studied using experimental investigations. It was observed that both load carrying capacity and stiffness of the encased stone column increased significantly with vacuum application. Also, application of vacuum accelerates rate of primary consolidation settlements. With this reduction in time, the construction activity can be accelerated which makes the project economically beneficial.INTRODUCTIONThe rising demand for the land for country’s infra-structure compels the engineers to work with even soft clay deposits which are not suitable for construction activities. As these soils have low bearing capacity and excessive settlement characteristics, ground improvement methods will be required before commencing construction. Among all available treatment methods, soil reinforcement and hydraulic modification technique are well-known popular techniques for its reduction in time required for consolidation settlement with improvement in load carrying capacity. When stone columns are used as a reinforcing member, it creates drainage with improves bearing capacity (Greenwood, 1970; Mitchell & Huber, 1983). However, the limitation includes lack of lateral confinement in very soft clay deposits, possibility of contamination, reduction in drainage path all which leads to the failure of stone columns (Mckenna et al, 1975). To overcome these limitations, encasement using geosynthetic material was adopted around the column which offers better lateral confinement, prevents intrusion of finer clay particle inside the column and provides effective drainage path with improved load bearing capacity characteristics (Van Impe, 1986; Raithel et al. 2005; Short et al. 2005; Borkemper et al. 2006; Murugesan & Rajagopal 2010; Kumar et al. 2014)"

Jan 1, 2017

By M. Ayhan

Drums of a modern longwall shearer are manufactured to include various constructional features conveying extracted material onto the face conveyor as efficiently as possible. Designing a drum with a conical shell or with reduced vane length, consequently with a stepper vane angle, is the most widely employed method in an attempt to increase loading efficiency. This study compares loading performances of two such drums, one having a conical shell with modified loading vanes, the other with a cylindrical shell with reduced vane length. Firstly, the loading performances of drums are predicted and the maximum haulage rate attainable with the drums are calculated. Then the performances of drum are compared by long-term comprehensive underground trials with coal shearers under similar conditions during the production operation of Park Termik Cayirhan coalmine in Turkey. Although higher loading performance is predicted for cylindrical drums, the in situ trials point out that Globoid drums have a slightly higher loading performance than cylindrical drums. Furthermore, the relationship between operational variables, i.e. extraction height, sumping depth, haulage rate and in situ loading performance, were investigated statistically on the basis of data gathered during the underground trials. Keywords: longwall mining, shearer drums, loading performance.

Jan 1, 2006